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Synthesis, Antitubercular and Anticancer Activities of Substituted Furyl-quinazolin-3(4H)-ones

✍ Scribed by Nulgulmnalli M. Raghavendra; Parameshwaran Thampi; Purvarga M. Gurubasavarajaswamy; Dharmarajan Sriram

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
302 KB
Volume
340
Category
Article
ISSN
0365-6233

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✦ Synopsis

Abstract

Some novel substituted‐3‐{[(1__E__)‐(substituted‐2‐furyl)‐methylene]amino}quinazolin‐4(3__H__)‐one (5, 6, 7) a–f were synthesized by a multi‐step process. These synthesized compounds are characterized by various spectroscopic techniques and evaluated for their antitubercular and anticancer activities. Biological activity indicated that some of the title compounds are potent antitubercular and anticancer agents.

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