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Synthesis of N 2 2‘-Deoxyguanosine Adducts Formed by 1-Nitropyrene

✍ Scribed by Chakraborti, Debasis; Colis, Laureen; Schneider, Renee; Basu, Ashis K.


Book ID
120552207
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
75 KB
Volume
5
Category
Article
ISSN
1523-7060

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Synthesis of biologically active N2-amin
✍ Radha R Bonala; Irina G Shishkina; Francis Johnson 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 147 KB

Several biologically important N 2 -adducts of 2 H -deoxyguanosine (dG) that previously were dicultly accessible, have been synthesized directly by means of the Buchwald±Hartwig reaction. The reaction employed in each case involves the coupling of 2 H -deoxy-2-bromoinosine with the appropriate amine