Synthesis of N2-(2-aminofluoren-3-yl) adducts of 2′-deoxyguanosine
✍ Scribed by Radha R Bonala; Pei-Lin Yu; Francis Johnson
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 125 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Several biologically important N 2 -adducts of 2 H -deoxyguanosine (dG) that previously were dicultly accessible, have been synthesized directly by means of the Buchwald±Hartwig reaction. The reaction employed in each case involves the coupling of 2 H -deoxy-2-bromoinosine with the appropriate amine
## Abstract For Abstract see ChemInform Abstract in Full Text.
The SO 4 --oxidation of cyclic 1,N 2 -propano-2%-deoxyguanosine, chemo-and regioselectively produced in the reaction of 2%-deoxyguanosine with excessive acetaldehyde or crotonaldehyde, resulted in the smooth formation of (4-hydroxy-5hydroxymethyltetrahydrofuran-2-ylimino)-(4-hydroxy-6-methyltetrahyd