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Synthesis of methylated phenylalanines via hydrogenolysis of corresponding 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids

✍ Scribed by MAJER, PAVEL ;SLANINOVÁ, JIŘINA ;LEBL, MICHAL

Book ID
115099603
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
610 KB
Volume
43
Category
Article
ISSN
0367-8377

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Synthesis of ethyl N-(diphenyl)methyl-1,
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A concise method for the synthesis of 1,2,3,4-tetrahydroisoquinoline-3-earboxylic acid derivatives from ot,tx'-dibromo-o-xylenes via sequential C-alkylation and N-alkylation of a glycine anion is described.