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Synthesis of Marine Natural Product (2S,5S)-Pyrrolidine-2,5-dicarboxylic Acid.

✍ Scribed by Gandavadi Sunilkumar; Dendukuri Nagamani; Narshinha P. Argade; Krishna N. Ganesh

Publisher
John Wiley and Sons
Year
2004
Weight
114 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

πŸ“œ SIMILAR VOLUMES

Organocatalytic Direct Asymmetric Mannic
Organocatalytic Direct Asymmetric Mannich Reactions of Hydroxyacetone by (2S,5S)-Pyrrolidine-2,5-dicarboxylic Acid
✍ Qing GU; Jing-Jing GONG; Jin FENG; Xin-Yan WU; Qi-Lin ZHOU πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 71 KB πŸ‘ 1 views

## Abstract The direct one‐pot three‐component asymmetric Mannich reactions of hydroxyacetone with anilines and benzaldehydes in the presence of (2__S__,5__S__)‐pyrrolidine‐2,5‐dicarboxylic acid afforded __syn__‐1,2‐amino alcohols in good‐to‐excellent yields (64% –95%) and up to 96% __ee__.