Organocatalytic Direct Asymmetric Mannic
β
Qing GU; Jing-Jing GONG; Jin FENG; Xin-Yan WU; Qi-Lin ZHOU
π
Article
π
2008
π
John Wiley and Sons
π
English
β 71 KB
π 2 views
## Abstract The direct oneβpot threeβcomponent asymmetric Mannich reactions of hydroxyacetone with anilines and benzaldehydes in the presence of (2__S__,5__S__)βpyrrolidineβ2,5βdicarboxylic acid afforded __syn__β1,2βamino alcohols in goodβtoβexcellent yields (64% β95%) and up to 96% __ee__.