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Synthesis of Leukotriene B3

✍ Scribed by Bernd Spur; Attilio Crea; Wilfried Peters; Wolfgang König

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
192 KB
Volume
318
Category
Article
ISSN
0365-6233

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✦ Synopsis

The synthesis of the highly chemotactic leukotriene B3 (la) and of its 6-trans isomer l b by Witrig reaction of the chiral phosphonium salt 3 with the aldehyde 4 is described. A new synthetic route to 4 starting from D-arabinose is reported.

Synthese voo Leukohien B,

Die Synthese des stark chemotaktischen Leukotrien B3 (la) und seines 6-rruns Isomers l b durch Winig Reaktion des chiralen Phosphoniumsalzes 3 mit dem Aldehyd 4 wird beschrieben. Ein neuer Syntheseweg zu 4 ausgehend von D-Arabinose wird aufgezeigt.

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