Total Synthesis of Leukotrienes from Butadiene
✍ Scribed by Ana Rodríguez; Miguel Nomen; Bernd W. Spur; Jean-Jacques Godfroid; Tak H. Lee
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 259 KB
- Volume
- 2000
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
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The synthesis of the highly chemotactic leukotriene B3 (la) and of its 6-trans isomer l b by Witrig reaction of the chiral phosphonium salt 3 with the aldehyde 4 is described. A new synthetic route to 4 starting from D-arabinose is reported. ## Synthese voo Leukohien B, Die Synthese des stark che
Quassinoids, a group of heavily oxygenated terpenoid bitter compounds isolated from the Simaroubaceae plant family, display a wide range of biological activities [1] and have attracted interest with respect to their synthesis during the past decades. [2] (À)-Samaderine Y (1), a pentacyclic quassinoi
Quassinoids, a group of heavily oxygenated terpenoid bitter compounds isolated from the Simaroubaceae plant family, display a wide range of biological activities [1] and have attracted interest with respect to their synthesis during the past decades. [2] (À)-Samaderine Y (1), a pentacyclic quassinoi