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ChemInform Abstract: Synthesis and Pharmacological Profile of New 1,3-Disubstituted Cyclohexanes as Leukotriene B4 Receptor Antagonists.

✍ Scribed by J. M. POUDREL; P. HULLOT; J. P. VIDAL; J. P. GIRARD; J. C. ROSSI; A. MULLER; C. BONNE

Publisher: John Wiley and Sons
Year: 2010
Weight: 32 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199707101

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✦ Synopsis

Synthesis and Pharmacological Profile of New 1,3-Disubstituted Cyclohexanes as Leukotriene B4 Receptor Antagonists.

-Novel non-aromatic members of stable leukotriene B4 antagonists such as (VIII) and (IX) are described, in which the conjugated double bond of the natural eicosanoid (X) is replaced by a 1,3-disubstituted cyclohexane ring.

-(POUDREL,

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