Synthesis of L-[1-13C]isoleucine via amidocarbonylation
✍ Scribed by Sun-Shine Yuan; Alfred M. Ajami
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- French
- Weight
- 276 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-2135
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## Abstract An improved synthesis of [1,1′‐^13^C~2~]‐L‐cystine which includes the optical resolution of the labeled N‐acetyl‐S‐benzyl‐DL‐cysteine by __Aspergillus__ acylase into __S__‐benzyl‐L‐cysteine is described.
## Abstract The stable, isotopically labelled amino acid __d__, 1‐1^13^C‐methionine, was prepared synthetically from 90% K^13^CN and 3‐(methylthio‐propionaldehyde. Chromatographic, infrared and mass spectrometric properties are presented which aid in the identification of this compound in body flui
## Abstract Synthesis of a [^13^C] tetrapeptide L‐[U‐^13^C]Lysyl‐L‐[1‐^13^C]Arginyl‐L‐[3‐^13^C]Aspartyl‐L‐[1‐^13^C] Serine (KRDS) on a __p__‐alkoxybenzyl ester polystyrene‐1% divinylbenzene resin support is described by using repetitive nonhydrolytic base cleavage of α‐amino protective groups in So