Synthesis of Ketones from α-Oxocarboxylates and Aryl Bromides by Cu/Pd-Catalyzed Decarboxylative Cross-Coupling

✍ Scribed by Lukas J. Gooßen; Felix Rudolphi; Christoph Oppel; Nuria Rodríguez

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 331 KB
• Volume: 47
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200705127

✦ Synopsis

The experiments in Table 2 were carried out on a 1.00-mmol scale in 20-mL septum-capped vessels. The products were purified by column chromatography (SiO 2 , hexane/ethyl acetate gradient) after aqueous workup.