Synthesis of Ketone from Alkyl Halide Using α-Chloro Nitrone as Oxidizing Reagent: A New Approach
✍ Scribed by Chakraborty, Bhaskar; Sharma, Prawin Kumar
- Book ID
- 120171632
- Publisher
- Taylor and Francis Group
- Year
- 2012
- Tongue
- English
- Weight
- 270 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0039-7911
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📜 SIMILAR VOLUMES
Tetrakis(dimethylamino)ethylene (TDAE) was found to be an effective reductant of chlorodifluoromethylated ketones 1-3. The generated ~,~-difluoroacetyl anion was trapped with several aldehydes 4-7, under mild conditions, to give the corresponding 2,2-difiuoro-3-hydroxy ketone derivatives 8-13, in mo
Tetrakis(dimethylamino)ethylene (TDAE) as a Useful Reductant of Some Chlorodifluoromethylated Ketones. A New Approach for the Synthesis of α,α-Difluoroketone Derivatives. -Reduction of chlorodifluoromethylated ketones with TDAE as an effective reductant generates α,α-difluoroacetyl anions, which ar