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Synthesis of isoxazolines and isoxazoles via generation of nitrile oxides from O-stannyl aldoximes

✍ Scribed by Moriya, Osamu; Takenaka, Hideo; Urata, Yoshikiyo; Endo, Takeshi


Book ID
121493697
Publisher
The Royal Society of Chemistry
Year
1991
Tongue
English
Weight
191 KB
Volume
23
Category
Article
ISSN
0022-4936

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πŸ“œ SIMILAR VOLUMES


Efficient synthesis of isoxazoles and is
✍ Sandeep Bhosale; Santosh Kurhade; Uppuleti Viplava Prasad; Venkata P. Palle; Deb πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 French βš– 417 KB

Treatment of aldoximes 1 with Magtrieve TM (CrO 2 ) in presence of dipolarophile 3 or 4, furnished a variety of isoxazolines 5a-u and isoxazoles 6a-q as 1,3-dipolar cycloaddition (1,3-DC) products (38 examples; 63-90% isolated yields). In situ formation of a nitrile oxide intermediate was confirmed

Solution-phase combinatorial synthesis o
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An efficient way to construct a library of isoxazoles and isoxazolines was developed by solution-phase 1,3-dipolar cycloaddition reaction of nitrile oxides with olefins and alkynes followed by precipitation of the products as HCl salts.