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Enhanced rate of intramolecular nitrile oxide cycloaddition and rapid synthesis of isoxazoles and isoxazolines

✍ Scribed by Brindaban Roy; Rajendra Narayan De


Publisher
Springer Vienna
Year
2010
Tongue
English
Weight
436 KB
Volume
141
Category
Article
ISSN
0026-9247

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An efficient way to construct a library of isoxazoles and isoxazolines was developed by solution-phase 1,3-dipolar cycloaddition reaction of nitrile oxides with olefins and alkynes followed by precipitation of the products as HCl salts.