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Synthesis of irigenin and of tectorigenin, derivatives of 5,7-dihydroxy-6-methoxyisoflavone

✍ Scribed by W. Baker; D.F. Downing; A.J. Floyd; B. Gilbert; W.D. Ollis; R.C. Russell

Publisher: Elsevier Science
Year: 1960
Tongue: French
Weight: 201 KB
Volume: 1
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)82687-3

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✦ Synopsis

OF the twenty-one known natural isoflavones,' three, tectorigenin, irigenin, and caviunin, are derivatives of 5,7-dihydroxy-6-methoqyisoflevone. This particular orientation of substituents makes a direct synthesis difficult, but a method, which we believe to be general, for the synthesis of such isoflavones is now described in the cases of tectorigenin and irigenin. Tectorigenin has previously been synthesised, 2 but it is of interest to note that irigenin, although it ' ?i. K. :;'o.rburton Quart. Rev. & 67 (1954). K. Venkataraman~ Fortschritte der Chem. Org. Nat. I& 1 ( 1959).

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