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Synthesis of 4′,7-Dihydroxy-6-methoxyisoflavone 7-O-β-d-Glucopyranoside (Glycitin)

✍ Scribed by Nógŕdi, Mihály ;Szöllosy, Áron

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
181 KB
Volume
1996
Category
Article
ISSN
0947-3440

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✦ Synopsis

Abstract

The aglycone glycitein (1) of the title glucoside glycitin (2) was prepared by oxidative rearrangement of the fully protected chalcone 4 by Tl(NO~3~)~3~ in MeOH into 5 followed by deprotection and ring closure. Its glucosylation with α‐acetobromoglucose and subsequent saponification gave 2 as the main product.

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