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Synthesis of Indolosulfonylureas, Potent Acetolactate Synthase Inhibitors.

✍ Scribed by Ye Zhang; Tianrui Ren


Book ID
101999622
Publisher
John Wiley and Sons
Year
2007
Weight
18 KB
Volume
38
Category
Article
ISSN
0931-7597

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In view of the isosterism of the sulfonyl group(-SO 2 -) and the phosphoryl group, two new types of compounds N-(N-aryl-O-alkyl phosphoryl)-NЈ-(4,6dimethoxypyrimidin-2-yl) ureas (2) and N-(N-aryl-Nalkylphosphoryl) -NЈ -(4, 6 -dimethoxypyrimidin -2-yl) ureas (3) were designed and synthesized by treat