𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of Imino Sugar Scaffolds for the Generation of Glycosidase Inhibitor Libraries

✍ Scribed by Barbara La Ferla; Piergiuliano Bugada; Laura Cipolla; Francesco Peri; Francesco Nicotra


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
389 KB
Volume
2004
Category
Article
ISSN
1434-193X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis of Pyrrolidine-Based Imino Sug
✍ Venkata Ramana Doddi; Yashwant D. Vankar 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 1 views

## Abstract Two pyrrolidine‐based imino sugars have been synthesized in an efficient manner, using regiospecific amination, ring closing metathesis, and diastereospecific dihydroxylations as key steps. These azasugars are found to be moderate inhibitors of glycosidases. (© Wiley‐VCH Verlag GmbH & C

A Parallel Synthesis Scheme for Generati
✍ Heike Strobel; Laurence Dugué; Philippe Marlière; Sylvie Pochet 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 438 KB 👁 1 views

We report a combinatorial approach aimed at producing in a single step a large family of nucleoside triphosphate derivatives that could be tested for their ability to be substrates for DNA polymerases. We propose as a unique triphosphate building block a nucleotide with a hydrazine function anchored