## Abstract For Abstract see ChemInform Abstract in Full Text.
Synthesis of hydrazinopeptides using solid phase N-amination. Application to chemical ligation
✍ Scribed by Christine Kiinguer; Oleg Melnyk; Estelle Loing; Hélène Gras-Masse
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 188 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
N-Methyl amino acids and their Fmoc derivatives are synthesized in high yield and purity on solid support using the Fukuyama amine synthesis protocol.
A novel and simple solid phase synthesis ofunsymme~cal secondary amines was developed. The general methodology was applied to the synthesis of arylethanolamines and arylpropanolamines.
The synthesis of Boc-or Fmoc-monoprotected propylenediamine derivatives is reported starting from N-protected a-amino acids. The introduction of these building blocks on solid support via the formation of a urea moiety leads to a new pseudopeptide family (Ca-CHe-CH~-Na(R)-CO-NH-Ca). Two carbonylati
A mild, facile cleavage of appropriately substituted tertiary, benzylic amines with acid chlorides is desodbed for both solution and solid phase.