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Synthesis of highly substituted spiropyrrolidines via 1,3-dipolar cycloaddition reaction of N-metalated azomethine ylides

✍ Scribed by G Subramaniyan; R Raghunathan


Book ID
118549805
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
104 KB
Volume
57
Category
Article
ISSN
0040-4020

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One-pot synthesis of novel ferrocene grafted N-methyl-spiropyrrolidines has been accomplished in good yields through a facile 1,3-dipolar cycloaddition reaction of various azomethine ylide derived from ninhydrin and sarcosine with various ferrocene derivatives as dipolarophile. The regiochemical and