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Synthesis of Heterocyclic Thiourea Compounds with Amino Acid Side Chain as Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase.

โœ Scribed by T. K. Venkatachalam; F. M. Uckun


Publisher
John Wiley and Sons
Year
2006
Weight
19 KB
Volume
37
Category
Article
ISSN
0931-7597

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โœฆ Synopsis


Abstract

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## Abstract Two methods for the preparation of dialkylsubstituted dipyridazino[4,3โ€__b__:3โ€ฒ,4โ€ฒโ€__e__][1,4]diazepinones and dipyridazino[3,4โ€__b__:3โ€ฒ,4โ€ฒโ€__e__][1,4]diazepinones are reported. The new compounds were evaluated for their inhibitory effects against the replication of human immunodeficien