𝔖 Bobbio Scriptorium
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Synthesis of Symmetrical and Asymmetrical Phenethyl Thiourea Compounds as Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase.

✍ Scribed by T. K. Venkatachalan; F. M. Uckum


Publisher
John Wiley and Sons
Year
2005
Weight
15 KB
Volume
36
Category
Article
ISSN
0931-7597

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✍ Odonírio Abrahão-Júnior; Paulo G. B. D. Nascimento; Sérgio E. Galembeck 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB

## Abstract TIBO (Tetrahydro‐imidazo[4,5,1‐jk][1,4]‐benzodiazepin‐2‐one) and nevirapine (11‐cyclopropyl‐5,11‐dihydro‐4‐methyl‐6H‐dipyrido[3,2‐b:2′,3′‐e][1,4]diazepin‐6‐one) are models for two classes of nonnucleoside inhibitors of the HIV‐1 virus reverse transcriptase (NNRTI). This work presents th