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Synthesis of Heterocyclic Crown Ethers by Intra- Versus Intermolecular 1,3-Dipolar Cycloaddition Reactions

✍ Scribed by Gerrit L'Abbé; Grete van Wuytswinkel; Wim Dehaen

Book ID
101763075
Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
115 KB
Volume
104
Category
Article
ISSN
0037-9646

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Diastereoselective synthesis of nicotine
Diastereoselective synthesis of nicotine derivatives via 1,3-dipolar cycloaddition reactions
✍ Mehdi Ghandi; Abuzar Taheri; Alireza Abbasi 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 339 KB

## Abstract magnified image A simple diastereoselective route to nicotine derivatives is presented. The one‐pot three component 1,3‐dipolar cycloaddition reaction of the Knöevenagel adducts of a number of aromatic aldehydes and malononitrile with an azomethine ylide derived __in situ__ from pyridin