1,3-Dipolar cycloaddition reactions. Regioselective synthesis of heterocycles and theoretical studies
โ Scribed by Adriana B. Pierini; Mario G. Cardozo; Aida A. Montiel; Sem M. Albonico; Maria T. Pizzorno
- Book ID
- 112129332
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1989
- Tongue
- English
- Weight
- 367 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0022-152X
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๐ SIMILAR VOLUMES
A facile synthesis of novel spiroindane-1,3-diones has been achieved via 1,3-dipolar cycloaddition of an azomethine ylide, generated in situ from ninhydrin and 1,2,3,4-tetrahydroisoquinoline, with the conjugated double bond of chalcone derivatives. The regiochemistry and structures of the cycloadduc
## Abstract Cycloaddition of an azomethine ylide, generated from ninhydrin and tetrahydroisoquinoline, with chalcones offers a novel diastereoselective synthesis of the target compounds.