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Synthesis of Heterocycle-Substituted 1-Aryl-4-piperidones.

✍ Scribed by Baihua Hu; Michael Malamas; John Ellingboe

Publisher
John Wiley and Sons
Year
2003
Weight
174 KB
Volume
34
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

πŸ“œ SIMILAR VOLUMES

A Facile Synthesis of N-Aryl Substituted
A Facile Synthesis of N-Aryl Substituted Piperidones
✍ Qian Geng; Hui Zhang; Weiguo Cao; Yali Chen πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 76 KB

## Abstract A general and efficient procedure for the synthesis of __N__‐aryl‐substituted 4‐piperidones was developed. The two step syntheses proceeded with an overall yield of 60%‐83% using __L__‐proline as the ligand for the Cu(I)‐catalyzed Ullmann amination followed by subsequent hydrolysis of r