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Synthesis of hapalosin and 8-deoxy-hapalosin

✍ Scribed by Björn Wagner; René Beugelmans; Jieping Zhu


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
198 KB
Volume
37
Category
Article
ISSN
0040-4039

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Synthesis and biological activities of h
✍ Nobuki Kashihara; Sakino To-e; Kensuke Nakamura; Kazuo Umezawa; Shosuke Yamamura 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 129 KB

AbstractÐAmong the hapalosin derivatives synthesized, the compounds carrying methyl (5a), methylthioethyl (5d) and phenylmethyl (5e) groups at the C12 position possess only the cis-peptide structure, in contrast to the cases of 5b and 5c. In addition to their conformational stability, the biological