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ChemInform Abstract: Total Synthesis of the Multidrug-Resistance Reversing Agent Hapalosin

โœ Scribed by Mansour Haddad; Candice Botuha; Marc Larcheveque

Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Confo
ChemInform Abstract: Synthesis and Conformational Analysis of the Multidrug Resistance- Reversing Agent Hapalosin (XIIIa) and Its Non-N-methyl Analogue (XIIIb) .
โœ T. Q. DINH; X. DU; R. W. ARMSTRONG ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 40 KB ๐Ÿ‘ 1 views

Synthesis and Conformational Analysis of the Multidrug Resistance-Reversing Agent Hapalosin (XIIIa) and Its Non-N-methyl Analogue (XIIIb) . -The key steps in the synthesis of (XIIIa) include two Brown allylboration reactions to obtain the chiral precursors (II) and (V) and macrolactonization of the