Synthesis of germanium derivatives of uracil and 5-fluorouracil
✍ Scribed by Katsumi Takakusaki; Norihiro Kakimoto; Yoshito Takeuchi; Shuji Tomoda
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 255 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Uracil nucleosides and nucleotides undergo a palladium catalyzed coupling reaction with styrenes to yield the respective 5-substituted derivatives.
## Abstract 3‐Alkylcarbonyloxymethyl derivatives of 5‐fluorouracil have been synthesized starting with 1‐ethyloxy‐carbonyl‐5‐fluorouracil. Alkylation of the starting material with alkylcarbonyloxymethyl iodides, generated from the corresponding chlorides by the Finkelstein reaction, in the presence
## Abstract The synthesis of 5‐[^3^H‐ethynyl]uracil and 5‐acetyl[6‐^3^H]uracil in good yield and of a medium specific activity ( > 40 mCi/mmol) is described. The compounds are necessary for following the incorporation of these and other derived 5‐substituted uracils into DNA and also for studying t
## Abstract 4′‐Substituted 1‐arylcarbonyl‐5‐fluorouracil derivatives were synthesized from the reaction of the potassium salt of 5‐fluorouracil with one equivalent of aryl acid chloride in acetonitrile. 4′‐Substituted 3‐arylcar‐bonyl‐5‐fluorouracil derivatives were synthesized from the reaction of