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Synthesis of 5-styryl derivatives of uracil nucleosides and nucleotides.

✍ Scribed by Christopher F Bigge; Panos Kalaritis; Mathias P Mertes

No coin nor oath required. For personal study only.

✦ Synopsis

Uracil nucleosides and nucleotides undergo a palladium catalyzed coupling reaction with styrenes to yield the respective 5-substituted derivatives.

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