Microwave-Assisted Synthesis of O′-Adamantylated Uracil-Derived Nucleosides.
✍ Scribed by Agata Gorska; Mariola Andrzejewska; Jaroslaw Kaminski; Zygmunt Kazimierczuk
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 97 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
📜 SIMILAR VOLUMES
Uracil nucleosides and nucleotides undergo a palladium catalyzed coupling reaction with styrenes to yield the respective 5-substituted derivatives.
## Abstract A series of pyridone derivatives were synthesized by the reaction of aromatic aldehydes, 1,3‐dicarbonyl compounds and ammonium acetate under microwave irradiation in the absence of solvent. The reactions were completed within __3‐__5 min to give the desired products in 72.4‐86.2% yields
Microwave-assisted bismesylate amination is an efficient method of synthesizing pyrrolidine ring derivatives and provides a good to excellent product yield.