## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
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Synthesis of Fused Sulfonamide (1,1-Dioxoisothiazole)substituted 1,5-Diarylpyrazoles as Cyclooxygenase Inhibitors.
β Scribed by Manojit Pal; Venugopal Rao Veeramaneni; Sanjeev Kumar; Vidya B. Lohray; Koteswar Rao Yeleswarapu
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 21 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide (SC-58635, Celecoxib). -Claisen condensation, followed by regioselective reaction with the hydrochloride