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Synthesis of Functionalized 7-Azaindoles via Directed ortho-Metalations.

✍ Scribed by Alexandre L'Heureux; Carl Thibault; Rejean Ruel


Publisher
John Wiley and Sons
Year
2004
Weight
136 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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## Abstract The __endo__‐ and __exo__‐rim positions of deep‐cavity cavitand **1** were functionalized by directed __ortho__ metalation (D__o__M) procedures. A range of electrophilic quenchers led to hosts with ester, phenol and thioether functionality. In each case, a combination of host pre‐organi