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Total Synthesis of Pawhuskin C: A Directed ortho-Metalation Approach.

✍ Scribed by Jeffrey D. Neighbors; Maya S. Salnikova; David F. Wiemer


Publisher
John Wiley and Sons
Year
2005
Weight
9 KB
Volume
36
Category
Article
ISSN
0931-7597

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Synthesis of benzoxazole-[phenyl-13C6] b
✍ Volker Derdau πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 97 KB

## Abstract A new method for the preparation of benzoxazole‐[phenyl‐^13^C~6~] (**1**) starting from aniline‐[^13^C~6~] (**4**) has been developed involving directed __ortho__‐metalation (D__o__M) chemistry. The synthesis comprises four steps and an overall yield of 39% was obtained. Copyright Β© 200