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Synthesis of benzoxazole-[phenyl-13C6] by directed ortho-metalation chemistry

✍ Scribed by Volker Derdau

Publisher: John Wiley and Sons
Year: 2004
Tongue: French
Weight: 97 KB
Volume: 47
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.792

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✦ Synopsis

Abstract

A new method for the preparation of benzoxazole‐[phenyl‐^13^C~6~] (1) starting from aniline‐[^13^C~6~] (4) has been developed involving directed ortho‐metalation (D__o__M) chemistry. The synthesis comprises four steps and an overall yield of 39% was obtained. Copyright © 2003 John Wiley & Sons, Ltd.

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