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Synthesis of Fluorosugar Analogues of 2,5,6-Trichloro-1-(β- d -ribofuranosyl)benzimidazole as Antivirals with Potentially Increased Glycosidic Bond Stability

✍ Scribed by Gudmundsson, Kristjan S.; Freeman, George A.; Drach, John C.; Townsend, Leroy B.


Book ID
117997776
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
84 KB
Volume
43
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Synthesis and Antiv
✍ K. S. GUDMUNDSSON; J. C. DRACH; L. L. WOTRING; L. B. TOWNSEND 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

Synthesis and Antiviral Activity of Certain 5'-Modified Analogues of 2, 5,6-Trichloro-1-(β-D-ribofuranosyl)benzimidazole (TCRB). -All 18 title compounds, e.g. ( Ib) and (Ic), show significant activity against human cytomegalovirus, some of them similar to lead compound TCRB (Ia), but only little to