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Synthesis and Antiviral Evaluation of Polyhalogenated Imidazole Nucleosides: Dimensional Analogues of 2,5,6-Trichloro-1-(β- d -ribofuranosyl)benzimidazole

✍ Scribed by Chien, Tun-Cheng; Saluja, Sunita S.; Drach, John C.; Townsend, Leroy B.


Book ID
120585396
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
184 KB
Volume
47
Category
Article
ISSN
0022-2623

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Synthesis and Antiviral Activity of Certain 5'-Modified Analogues of 2, 5,6-Trichloro-1-(β-D-ribofuranosyl)benzimidazole (TCRB). -All 18 title compounds, e.g. ( Ib) and (Ic), show significant activity against human cytomegalovirus, some of them similar to lead compound TCRB (Ia), but only little to