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Synthesis of fatty 2-oxazolines from fatty methyl 2,3-epoxy ester

✍ Scribed by M. H. Ansari; M. Ahmad

Book ID
112775883
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
869 KB
Volume
63
Category
Article
ISSN
0003-021X

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Selective synthesis of 2-chloro-2,3-epox
Selective synthesis of 2-chloro-2,3-epoxy-2-oxazolines and isomeric 3-chloro-2-oxo-2-oxazolines
✍ Jean Claude Combret; Abdelhamid Meghni; Didier Postaire; Jacques Tekin πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 French βš– 219 KB

The reaction of 2-dichloromethyl-4,4-dimethyl-2-oxazoline with carbonyl compounds in basic media has been investigated. Phase transfer catalysis allows fast and selective formation of 2-chloro-2,3-epoxy-2-oxazolines (with aliphatic aldehydes) or 3-chloro-2-oxo-2-oxazolines (mainly with ketones) in h