𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of f-18 labelled fluoro-melatonins and 5-hydroxy-fluoro-tryptophans

✍ Scribed by Raman Chirakal; Brian G. Sayer; Gunter Firnau; E. S. Garnett

Publisher
John Wiley and Sons
Year
1988
Tongue
French
Weight
251 KB
Volume
25
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

S e c t i o n o f R a d i o l o g y a n d N u c l e a r M e d i c i n e and Department o f C h e m i s t r y , H a m i l t o n , O n t a r i o , Canada, L8N 325 SUHMARY R e a c t i o n o f d i l u t e [ F -l 8 ] f l u o r i n e gas w i t h e i t h e r m e l g t o n i n o r 5 -h y d r o x y -t r y p t o p h a n i n h y d r o g e n f l u o r i d e a t -7 0 C g i v e s 6 -f l u o r o -m e l a t o n i n o r 4and 6 -f l u o r o -5 -h y d r o x y t r y p t o p h a n . T h e y a r e o f p o t e n t i a l use i n P o s i t r o n E m i s s i o n Tomography t o image t h e b i n d i n g s i t e s f o r m e l a t o n i n and t o s t u d y t h e m e t a b o l i s m o f s e r o t o n i n .

📜 SIMILAR VOLUMES

Synthesis of fluorine-18-labelled 5- and
Synthesis of fluorine-18-labelled 5- and 6-fluoro-2-pyridinamine
✍ Aiman Abrahim; Peter Angelberger; Kurt Kletter; Markus Müller; Christian Joukhad 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 314 KB

## Abstract A one‐pot radiosynthesis method to prepare the new fluorine‐18‐labelled fluoropyridine derivatives 5‐[^18^F]fluoro‐2‐pyridinamine and 6‐[^18^F]fluoro‐2‐pyridinamine in two to three reaction steps was developed. The first step consisted of no‐carrier‐added nucleophilic aromatic substitut

Synthesis of 6-[18F]fluorodopamine, 6-[1
Synthesis of 6-[18F]fluorodopamine, 6-[18F]fluoro-m-tyramine and 4-[18F]fluoro-m-tyramine+
✍ Mohammad Namavari; N. Satyamurthy; Jorge R. Barrio 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 376 KB

## Abstract A new method for the preparation of 6‐[^18^F]fluorodopamine (3) and [^18^F]fluorinated analogs of __m__‐tyramine based on a regioselective radiofluorodestannylation reaction has been developed. The radiofluorodestannylation of 6‐trimethylstannyldopamine derivative 1 was carried out with

Synthesis of [18F]-labeled 2′-deoxy-2′-f
Synthesis of [18F]-labeled 2′-deoxy-2′-fluoro-5-methyl-1-β-D-arabinofuranosyluracil ([18F]-FMAU)
✍ Mian M. Alauddin; Peter S. Conti; John D. Fissekis 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 100 KB 👁 1 views

## Abstract Synthesis of 2′‐deoxy‐2′‐[^18^F]fluoro‐5‐methyl‐1‐__β__‐D‐arabinofuranosyluracil ([^18^F]‐FMAU) is reported. 2‐Deoxy‐2‐[^18^F]fluoro‐1,3,5‐tri‐O‐benzoyl‐__α__‐D‐arabinofuranose **2** was prepared by the reaction of the respective triflate **1** with tetrabutylammonium[^18^F]fluoride. Th