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Synthesis of Esculentin-1 Antibacterial Peptide Fragments on 1,4-Butanediol Dimethacrylate Cross-Linked Polystyrene Support

✍ Scribed by M. Roice; G. Suma; K. S. Kumar; V. N. Rajasekharan Pillai


Book ID
110296910
Publisher
Springer
Year
2001
Tongue
English
Weight
90 KB
Volume
20
Category
Article
ISSN
1573-4943

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πŸ“œ SIMILAR VOLUMES


Optimization in Peptide Synthetic Condit
✍ M Roice; K.S Kumar; V.N Rajasekharan Pillai πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 227 KB

AbstractÐA 1,4-butanediol dimethacrylate cross-linked polystyrene (PS±BDODMA) support was prepared by aqueous suspension polymerization. The C-terminal amino acid incorporation, N a -Fmoc and Boc-deprotection, acylation reactions and the removal of the target peptide from the support were optimized.

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The synthesis of three hydrophobic peptides, which are partial sequences of thioredoxin, on a newly developed, flexible 1,6-hexanediol diacrylate cross-linked polystyrene, in good yield and purity, is described.