Synthesis of epibatidine
β Scribed by Kazimir Sestanj; Edward Melenski; Ivo Jirkovsky
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 227 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
A total synthesis of racemic epibatidine, a natural product with analgesic activity, is described. Distinctly different from the previously published routes it starts from simple, known alkaloid in six steps.
π SIMILAR VOLUMES
A synthesis of the non-opiate analgesic alkaloid epibatidine was achieved in 13 steps and 13% overall yield starting from 1,3-cyclohexadiene using in a key step a modified Stille coupling reaction on an c~-iodocyclohexenone.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v