Synthesis of Enantiopure 2-Amino-1-phenyl and 2-Amino-2-phenyl Ethanols Using Enantioselective Enzymatic Epoxidation and Regio- and Diastereoselective Chemical Aminolysis.
β Scribed by Guido Sello; Fulvia Orsini; Silvana Bernasconi; Patrizia Di Gennaro
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 22 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Phenyl-piperazinomethyl-amino-oxazoline 3. labelled with carbon-14 was obtained in good yield in two steps from [14CIepichlorhydrin. Specific radioactivity: 19.40 PCilmg; 5,09 mCilmmo1. Radiochemical yield: 50 % of the theoretical amount.