Aziridines / Oxazolines / Ring expansion reactions / α-Hydroxy β-amino acids / β-Hydroxy α-amino acids A new method for the preparation of 2,2,3-trisubstituted methyl 1-benzoylaziridine-2-carboxylates is reported. These compounds have been obtained starting from α-alkyl βamino acids by formation of
Synthesis of E and Z 1-amino-2-aryl(alkyl)-cyclopropanecarboxylic acids via meldrum derivatives
✍ Scribed by M.L. Izquierdo; I. Arenal; M. Bernabé; E. Fernández Alvarez
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- French
- Weight
- 557 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4020
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## Abstract Starting from 5‐bismethylthiomethylene Meldrum's acid, the synthesis of 5‐diaminomethylene Meldrum's acids and 2‐aminoquinolone derivatives, structurally related to potassium channels openers pinacidil and diazoxide, is described.
## Abstract A series of dihydropyrazolo[3,4‐__b__]pyridin‐6‐ones 3 was prepared by cyclization of 5‐amino‐1‐aryl‐3‐methylpyrazoles 1 and Meldrum's acid benzylidene derivatives 2 in nitrobenzene. The structure of 4,5‐dihydropyrazolo[3,4‐__b__]pyridin‐6‐ones and reaction orientation were determined b