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Synthesis of 2-amino-1,4-dihydro-4-quinolinones and diaminomethylene meldrum's acids derivatives as potential potassium channel openers

✍ Scribed by Béanéadicte Erb; Benoît Rigo; Bernard Pirotte; Daniel Couturier

Publisher: Journal of Heterocyclic Chemistry
Year: 2002
Tongue: English
Weight: 158 KB
Volume: 39
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570390102

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✦ Synopsis

Abstract

Starting from 5‐bismethylthiomethylene Meldrum's acid, the synthesis of 5‐diaminomethylene Meldrum's acids and 2‐aminoquinolone derivatives, structurally related to potassium channels openers pinacidil and diazoxide, is described.

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