ChemInform Abstract: Synthesis of Some 4-[3′ or 4′-(4H-4-Oxo-1-benzopyran-2-yl)phenyl]-1,4-dihydropyridine Derivatives as Potential Calcium Channel Antagonists.
✍ Scribed by M. Tuncbilek; R. Ertan
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Synthesis of Some 4-[3' or 4'-(4H-4-Oxo-1-benzopyran-2-yl)phenyl]-1,4-dihydropyridine Derivatives as Potential Calcium Channel Antagonists. -A series of new flavonoid derivatives bearing a dihydropyridine moiety on the phenyl ring [cf. (IV), (VII), 23 examples] are prepared. Compound (IVa) exhibits calcium channel antagonist activity comparable with nifedipine.
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