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Synthesis of double 15N-labeled nitramines: N-nitropiperidine and N-nitrodimethylamine

✍ Scribed by S. Bulusu; J. Autera; T. Axenrod

Publisher
John Wiley and Sons
Year
1980
Tongue
French
Weight
172 KB
Volume
17
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Double ^15^N‐labeled N‐nitropiperidine and N‐nitrodimethylamine have been conveniently prepared by oxidation of the corresponding nitrosamines. Dimethylamine‐^15^N was commercially available while the required piperidine‐^15^N was synthesized from cyclopentanone via the Schmidt ring‐expansion procedure using potassium azide‐1‐^15^N, followed by hydride reduction of the resulting 2‐piperidinone‐^15^N.

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