Synthesis of DNA fragments containing 5-methyl-deoxycytidine residues
β Scribed by G. A. van der Marel; G. Wille; H. Westerink; A. H.-J. Wang; A. Rich; J. R. Mellema; C. Altona; J. H. van Boom
- Book ID
- 104588402
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 195 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0165-0513
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β¦ Synopsis
Abstract
A properly protected 5βmethylated deoxycytidine (5mC) derivative has been synthesized and applied to assemble DNA fragments containing 5mCG, 5mCC and 5mC5mC sequences.
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Morpholino phosphorobis-3-nitro-1,2,4\_triazolidate (L) has been applied to the phosphorylation of partially protected (5'-OH free) DNA intermediates (2). Using this procedure, the following types of compounds were synthesized: ~B~(BP)~B; APPBP(BP)~B and PPBP(BP),B. The synthesis of DNA fragments (i