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Chemical and Enzymatic Synthesis of DNA Fragments Containing 5-(β-D-Glucopyranosyloxymethyl)-2′-deoxycytidine − a Modified Nucleoside in T4 Phage DNA

✍ Scribed by Martin de Kort; Peter C. de Visser; Jürgen Kurzeck; Nico J. Meeuwenoord; Gijs A. van der Marel; Wolfgang Rüger; Jacques H. van Boom

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
424 KB
Volume
2001
Category
Article
ISSN
1434-193X

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ChemInform Abstract: Chemical and Enzyma
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✍ Martin de Kort; Peter de Visser; Juergen Kurzeck; Nico J. Meeuwenoord; Gijs A. v 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB

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Synthesis of Oligodeoxynucleotides Conta
Synthesis of Oligodeoxynucleotides Containing 5-(β-D-Glucopyranosyloxymethyl)-2′-deoxyuridine, a Modified Nucleoside in the DNA of Trypanosoma Brucei
✍ Martin de Kort; Edwin Ebrahimi; Eric R. Wijsman; Gijs A. van der Marel; Jacques H. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 257 KB

The synthesis of the recently discovered modified DNA base derivative 20, readily available from thymidine in 48%, afforded the fully protected nucleoside 22 in 96% yield. The 5-(β-D-glucopyranosyloxymethyl)-2Ј-deoxyuridine (β-dJ, 1) is described. TMSOTf mediated β-glucosylation of latter compound w