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Synthesis of Dimeric Trifluoromethoxyacridine-Derived Pathogen-Inactivating Nucleic Acid Intercalators.

✍ Scribed by Rene Csuk; Christian Raschke; Gunnar Goethe; Stefan Reissmann

Book ID
101971048
Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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Synthesis of Dimeric Trifluoromethoxyacr
Synthesis of Dimeric Trifluoromethoxyacridine-derived Pathogen-inactivating Nucleic Acid Intercalators
✍ René Csuk; Christian Raschke; Gunnar Göthe; Stefan Reißmann 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB

## Abstract A series of antiviral active compounds consisting of an intercalating acridine‐derived part, a spacer region and a reactive EDTA‐derived conjugate was synthesized in an easy sequence. Thus, suitably mono‐protected 1, ω‐alkyldiamines gave, upon reaction with 9‐chloro‐2‐trifluoromethoxyac