Synthesis of hybrid bisnucleoside 5′, 5‴
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Thomas W. Traut
📂
Article
📅
1987
🏛
Springer
🌐
English
⚖ 490 KB
Aminoacyl tRNA synthetases, by means of a back reaction, are able to synthesize certain 5', 5"'-P1, P4-bisnucleoside tetraphosphates of biological importance, such as Ap4A. Here it is shown that HisRS and TrpRS (Bacillus stearothermophilus) and AlaRS (E. coli) also synthesize the hybrid compounds Ap