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Synthesis of deuterium-labelled trantinterol

✍ Scribed by Hongliang Wen; Li Pan; Yingdan Zhang; Jiacheng Ma; Liqiong Qin; Maosheng Cheng

Publisher: John Wiley and Sons
Year: 2010
Tongue: French
Weight: 93 KB
Volume: 53
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.1796

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✦ Synopsis

Abstract

Trantinterol, a selective β~2~‐adrenoceptor agonist, is currently in Phase II clinical trials for the treatment of asthma and bronchitis. The synthesis of deuterium‐labelled trantinterol is described. The labelled trantinterol is used as an internal standard for the analysis and metabolic studies. Copyright © 2010 John Wiley & Sons, Ltd.

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